Healthcare & Biotech: Frontier Medicines named three drug-development veterans to expand its leadership team as it nears clinical milestones, including data expected at ESMO. Medical Research: A City of Hope study suggests cutting sugar during antibiotic treatment may help protect the gut microbiome for high-risk blood cancer patients. Illinois Health Policy/Regulation: Illinois is tightening Equal Pay Registration Certificate (EPRC) data standards, including changes to race/ethnicity reporting starting in January 2027. Medical Devices & Compliance: ICUS challenged a widespread “state law” misconception about sonographers administering IVs and ultrasound contrast, and filed FDA citizen petitions to broaden contrast-enhanced ultrasound uses and remove outdated “black box” warnings. Chicago Business & Governance: Chicago passed a rule requiring a larger majority of aldermen to approve new city borrowing, a move aimed at slowing debt growth. Public Safety/Local Economy: Police are investigating an isolated shooting at Oakbrook Center; the mall remains open. Trade & Enforcement: U.S. Customs seized 200 counterfeit Cartier watches worth $28 million at O’Hare. Higher Education & Philanthropy: Ken Griffin’s $3 billion gift to Carnegie Mellon is driving a major expansion, including a new Miami campus. Sports Business/Local Interest: The Chicago Bears opened a 21-day practice window for DB Kyler Gordon as the team prepares for the Jets.